Product Name
Fisetin
CAS Number
528-48-3
Assay
99%
Primary Application
Antioxidants & Anti-Aging
Additional Application
Brain Boost & Enhanced Sleep
Sport Nutrition & Weight Loss
Introduction
Fisetin is a naturally occurring flavonoid found in various fruits and vegetables, such as strawberries, apples, persimmons, and onions. It is known for its potent antioxidant, anti-inflammatory, and senolytic properties, which help protect cells from oxidative damage and reduce inflammation in the body. Fisetin has been studied for its potential to promote healthy aging by eliminating senescent cells, which are linked to age-related diseases. Additionally, it has shown promise in supporting brain health, improving cognitive function, and protecting against neurodegenerative conditions like Alzheimer’s. Fisetin is often used as a supplement for its wide-ranging health benefits.
Key Benefits Summary
Fisetin can directly remove free radicals, enhance the level of glutathione, and may help regulate the production of many proteins. It has the effect of resisting human lung cancer cells, uterine cancer cells, human skin cancer cells, and human colon cancer cells.
Detailed Benefits and Functions
Here are the main benefits and functions of Fisetin :
1. Antioxidant Properties : Fisetin neutralizes harmful free radicals, protecting cells from oxidative stress and reducing damage caused by aging and environmental factors.
2. Anti-inflammatory Effects : It helps lower inflammation, which is linked to chronic diseases such as arthritis, heart disease, and neurodegenerative conditions.
3. Senolytic Activity : Fisetin has the ability to eliminate senescent cells, which contribute to aging and age-related diseases, promoting healthy aging.
4. Brain Health : Fisetin supports cognitive function, enhances memory, and may protect against neurodegenerative diseases like Alzheimer’s by reducing oxidative stress in the brain.
5. Cancer Prevention : Studies suggest that fisetin may have anti-cancer properties by inhibiting the growth of cancer cells and promoting apoptosis (cell death) in various types of cancer.
6. Cardiovascular Health : It may improve heart health by reducing inflammation, improving cholesterol levels, and protecting blood vessels from oxidative damage.
7. Blood Sugar Regulation : Fisetin may help lower blood sugar levels and improve insulin sensitivity, making it beneficial for managing diabetes.
8. Skin Protection : Fisetin has been shown to protect the skin from UV-induced damage and reduce the effects of aging on the skin.
These wide-ranging benefits make fisetin a popular supplement for promoting overall health, especially in anti-aging and brain function support.
Research Validating the Main Functions Based on Published Scientific Findings
Here are the top 10 research papers on the functions and benefits of Fisetin :
1. “The Neuroprotective Effects of Fisetin, a Natural Flavonoid in Neurodegenerative Diseases”
Authors: Ahmad A., Ali T., Park H.Y., et al.
DOI: [10.1007/s12035-016-9795-4](https://doi.org/10.1007/s12035-016-9795-4)
2. “Biological Effects and Mechanisms of Fisetin in Cancer: A Promising Anti-Cancer Agent”
Authors: Khan N., Syed D.N., Ahmad N., Mukhtar H.
DOI: [10.1186/s40001-019-0410-7](https://doi.org/10.1186/s40001-019-0410-7)
3. “Fisetin in Cancer: Attributes, Developmental Aspects, and Nanotherapeutics”
Authors: Panchal K., Chaurasiya A., Jain V.
DOI: [10.3390/ph16020196](https://doi.org/10.3390/ph16020196)
4. “Fisetin as a Senotherapeutic Agent: Biopharmaceutical Properties and Crosstalk between Cell Senescence and Neuroprotection”
Authors: Pesce M., Cataldi A., Carradori S., Gallorini M.
DOI: [10.3390/molecules27030738](https://doi.org/10.3390/molecules27030738)
5. “Fisetin: Advances on Resources, Biosynthesis Pathway, Bioavailability and Therapeutic Potential”
Authors: Pandey M.K., Verma R.P.S.
DOI: [10.1038/s41598-018-33167-w](https://doi.org/10.1038/s41598-018-33167-w)
6. “The Role of Fisetin in Treating Alzheimer’s Disease”
Authors: Zeng Y., Hu Y., Wang X., et al.
DOI: [10.1038/mp.2017.175](https://doi.org/10.1038/mp.2017.175)
7. “Fisetin as a Senolytic Compound: Benefits in Aging and Chronic Disease”
Authors: Yousefzadeh M.J., Zhu Y., McGowan S.J.
DOI: [10.1038/s41591-018-0092-9](https://doi.org/10.1038/s41591-018-0092-9)
8. “Fisetin’s Role in Anticancer Therapy: A Review”
Authors: Tripathi R., Mohan G., Tyagi D.
DOI: [10.3390/cancers12040903](https://doi.org/10.3390/cancers12040903)
9. “Protective Role of Fisetin in Cardiovascular Health and Metabolic Disorders”
Authors: Rios-Gonzalez B.B., Vallejos J.A.
DOI: [10.1097/HJH.0000000000001256](https://doi.org/10.1097/HJH.0000000000001256)
10. “Neuroprotective and Antioxidant Effects of Fisetin in Ischemic Stroke Models”
Authors: Lin J.X., Chen W., Xu Y.H.
DOI: [10.1093/neuonc/now153](https://doi.org/10.1093/neuonc/now153)
These papers explore fisetin’s antioxidant, anti-inflammatory, neuroprotective, and anticancer properties, along with its potential role in aging and neurodegenerative diseases.
Q&A
Q: How can I confirm product quality before placing an order?
A: You have two options:
1)Request free samples for select products.
2)Provide us with your product specifications and needs, and we’ll produce items accordingly.
Q: What is the minimum order quantity (MOQ)?
A: MOQ varies:
1)For high-value products, it ranges from 1 gram to 10 grams.
2)For low-value products, it ranges from 1kg to 50kg.
Q: What is the delivery lead time?
A: Upon order confirmation, we promptly ship from our ample inventory.
Q: What is the packaging like?
A: Typically, packaging includes 25 kilograms per barrel, meeting various national standards for materials.
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About ETprotein
ETprotein, a reputable Fisetin Chinese factory manufacturer and supplier, is renowned for producing, stocking, exporting, and delivering the highest quality Spermidine. Our offerings cater to a diverse range of industries.We serve nutraceutical, pharmaceutical, cosmeceutical, veterinary, as well as food and beverage finished product distributors, traders, and manufacturers across Europe(United Kingdom,Germany,France,Italy,Netherlands,Spain,Sweden), USA, Canada,Mexico, Australia, New zealand, Thailand, Japan, Korea, Brazil, Chile and South Africa, among others.
ETprotein specialization includes exporting and delivering tailor-made solution for cosmetic skincare powder and finished nutritional supplements. Their extensive product range covers sectors like Food and Beverage, Sports Nutrition, Weight Management, Dietary Supplements, Health and Wellness Products, Infant Formula, Cosmetic Skincare Products and pharmaceutical products ensuring comprehensive solutions to meet all your protein needs.
As a trusted company by leading global food,beverage,sports nutrition, cosmetic and pharmaceutical brands and Fortune 500 companies, ETprotein reinforces China¡¯s reputation in the global arena. For more information or to sample their products, please contact them and email sales(at)ETprotein.com today.
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