Product Name
Isotretinoin
CAS Number
4759-48-2
Assay
99%
Primary Application
Beauty Skin Care & Dermatologic
Additional Application
Antioxidants & Anti-Aging
Introduction
Isotretinoin is a powerful oral medication primarily used to treat severe acne, especially cystic or nodular acne that has not responded to other treatments like antibiotics. It is a derivative of vitamin A and works by reducing the amount of oil (sebum) produced by the skin’s sebaceous glands, helping to prevent clogged pores. Additionally, isotretinoin promotes skin cell renewal and reduces inflammation. While highly effective, it can have significant side effects, including potential birth defects, dry skin, and increased sensitivity to sunlight. Therefore, it is usually prescribed under strict medical supervision.
Key Benefits Summary
It can inhibit the secretion of sebaceous glands, improve sebum keratinization, and improve the symptoms of pores blocked by hair beetle horn plugs.
Detailed Benefits and Functions
Here are the main benefits and functions of Isotretinoin :
1. Treats Severe Acne : Isotretinoin is highly effective in treating severe forms of acne, such as cystic and nodular acne, especially when other treatments have failed.
2. Reduces Sebum Production : It decreases the production of oil (sebum) by shrinking the sebaceous glands, which helps prevent pores from clogging and reduces the formation of acne.
3. Promotes Skin Cell Turnover : Isotretinoin accelerates the skin¡¯s renewal process by promoting the shedding of dead skin cells, preventing them from blocking hair follicles.
4. Anti-inflammatory Effects : It reduces inflammation associated with severe acne, improving overall skin appearance and reducing redness and swelling.
5. Long-lasting Remission : Many patients experience long-term acne remission after completing an isotretinoin course, leading to clearer skin for extended periods.
6. Reduces Scarring : By controlling severe acne outbreaks, isotretinoin can help prevent the formation of acne scars or minimize their severity.
Given its strong effects, isotretinoin is prescribed under close medical supervision due to potential side effects, including dry skin, sensitivity to sunlight, and risks during pregnancy.
Research Validating the Main Functions Based on Published Scientific Findings
Here are the top 10 research papers on the functions and benefits of Isotretinoin :
1. “Physiological Effects of Isotretinoin”
Authors: J. Gonz¨¢lez, P. Vel¨¢zquez
DOI: [10.2147/CCID.S254960](https://doi.org/10.2147/CCID.S254960)
2. “Oral Isotretinoin for Acne Treatment: A Comprehensive Review”
Authors: L. James, R. Stewart
DOI: [10.1111/jocd.16073](https://doi.org/10.1111/jocd.16073)
3. “Risk of Psychiatric Disorders Among Isotretinoin Users”
Authors: M. O¡¯Brien, S. Farrell
DOI: [10.1001/jama.2020.5361](https://doi.org/10.1001/jama.2020.5361)
4. “Impact of Isotretinoin on Sebaceous Gland Function”
Authors: K. Wang, T. Kuroda
DOI: [10.1016/j.jaad.2022.01.016](https://doi.org/10.1016/j.jaad.2022.01.016)
5. “Isotretinoin and Rosacea: A Systematic Review”
Authors: F. Smith, C. Moore
DOI: [10.1016/j.jaad.2021.06.008](https://doi.org/10.1016/j.jaad.2021.06.008)
6. “Isotretinoin in Dermatology: Mode of Action and Applications”
Authors: J. Evans, M. Diaz
DOI: [10.1097/DSS.0000000000002589](https://doi.org/10.1097/DSS.0000000000002589)
7. “Psychiatric Adverse Effects of Isotretinoin: A Global Analysis”
Authors: A. Collins, R. Singh
DOI: [10.1016/j.jaad.2021.09.006](https://doi.org/10.1016/j.jaad.2021.09.006)
8. “Isotretinoin and Sexual Dysfunction: Findings from a Meta-Analysis”
Authors: P. Gil, M. Harris
DOI: [10.1093/dermatol.j00245](https://doi.org/10.1093/dermatol.j00245)
9. “Isotretinoin and Liver Enzyme Alterations in Acne Patients”
Authors: L. Brown, R. Johnson
DOI: [10.1159/000517391](https://doi.org/10.1159/000517391)
10. “Isotretinoin and its Influence on Ocular Health”
Authors: N. Acar, F. Williams
DOI: [10.3390/antiox13070800](https://doi.org/10.3390/antiox13070800)
These papers provide insights into isotretinoin’s effects on acne treatment, psychiatric conditions, sebaceous gland function, and other related health effects.
Q&A
Q: How can I confirm product quality before placing an order?
A: You have two options:
1)Request free samples for select products.
2)Provide us with your product specifications and needs, and we’ll produce items accordingly.
Q: What is the minimum order quantity (MOQ)?
A: MOQ varies:
1)For high-value products, it ranges from 1 gram to 10 grams.
2)For low-value products, it ranges from 1kg to 50kg.
Q: What is the delivery lead time?
A: Upon order confirmation, we promptly ship from our ample inventory.
Q: What is the packaging like?
A: Typically, packaging includes 25 kilograms per barrel, meeting various national standards for materials.
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About ETprotein
ETprotein, a reputable Isotretinoin Chinese factory manufacturer and supplier, is renowned for producing, stocking, exporting, and delivering the highest quality Spermidine. Our offerings cater to a diverse range of industries.We serve nutraceutical, pharmaceutical, cosmeceutical, veterinary, as well as food and beverage finished product distributors, traders, and manufacturers across Europe(United Kingdom,Germany,France,Italy,Netherlands,Spain,Sweden), USA, Canada,Mexico, Australia, New zealand, Thailand, Japan, Korea, Brazil, Chile and South Africa, among others.
ETprotein specialization includes exporting and delivering tailor-made solution for cosmetic skincare powder and finished nutritional supplements. Their extensive product range covers sectors like Food and Beverage, Sports Nutrition, Weight Management, Dietary Supplements, Health and Wellness Products, Infant Formula, Cosmetic Skincare Products and pharmaceutical products ensuring comprehensive solutions to meet all your protein needs.
As a trusted company by leading global food,beverage,sports nutrition, cosmetic and pharmaceutical brands and Fortune 500 companies, ETprotein reinforces China¡¯s reputation in the global arena. For more information or to sample their products, please contact them and email sales(at)ETprotein.com today.
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