Product Name
L-5-methyltetrahydrofolate calcium (Super Folic Acid)
CAS Number
151533-22-1
Assay
99%
Primary Application
Antioxidants & Anti-Aging
Beauty Skin Care & Dermatologic
Additional Application
Brain Boost & Enhanced Sleep
Introduction
L-5-Methyltetrahydrofolate calcium (L-5-MTHF-Ca) is the bioactive form of folate, a vital B-vitamin (B9) used in the body for DNA synthesis, methylation processes, and red blood cell formation. Unlike synthetic folic acid, L-5-MTHF is directly absorbed and utilized by the body without needing to be converted. This makes it especially beneficial for individuals with genetic mutations, such as MTHFR polymorphisms, which impair the body’s ability to process folic acid. L-5-MTHF plays a key role in supporting cardiovascular health, neurological function, and prenatal development by helping reduce homocysteine levels and supporting healthy fetal growth.
Key Benefits Summary
It is a very important vitamin in the human body and also an active folic acid. Its main role in the human body is to participate in the metabolic process of amino acids such as methionine and methionine, promote the synthesis and repair of DNA, and support the normal function of the nervous system.
Detailed Benefits and Functions
Here are the main benefits and functions of L-5-Methyltetrahydrofolate Calcium (L-5-MTHF-Ca) :
1. Active Folate Form : L-5-MTHF is the bioactive form of folate, bypassing the need for conversion from synthetic folic acid, making it readily usable by the body.
2. Supports DNA Synthesis and Methylation : It plays a key role in DNA synthesis, repair, and methylation, processes essential for cell division and growth.
3. Reduces Homocysteine Levels : L-5-MTHF helps convert homocysteine to methionine, reducing elevated homocysteine levels, which are linked to cardiovascular disease.
4. Improves Cardiovascular Health : By lowering homocysteine levels, it helps protect against heart disease and other cardiovascular conditions.
5. Supports Prenatal Health : It is crucial for fetal development, especially in reducing the risk of neural tube defects during pregnancy.
6. Beneficial for MTHFR Polymorphisms : People with MTHFR gene mutations struggle to convert folic acid into its active form. L-5-MTHF provides a direct and efficient source of active folate for these individuals.
7. Neurological Support : Adequate levels of L-5-MTHF support cognitive function, nerve health, and may reduce the risk of neurological disorders.
8. Enhances Mood Regulation : L-5-MTHF is involved in neurotransmitter synthesis, which supports mental health by contributing to serotonin and dopamine production, potentially improving mood regulation.
These benefits make L-5-MTHF-Ca an important supplement for individuals who need a more bioavailable form of folate, particularly for cardiovascular and prenatal health.
Research Validating the Main Functions Based on Published Scientific Findings
Here are the top 10 research papers on the functions and benefits of L-5-Methyltetrahydrofolate Calcium (L-5-MTHF-Ca) :
1. “Folic Acid vs. L-5-Methyltetrahydrofolate: A Narrative Review on Bioavailability and Clinical Efficacy”
Authors: Montero-Bravo A.M., Partearroyo T., Varela-Moreiras G.
DOI: [10.3390/nu16183154](https://doi.org/10.3390/nu16183154)
2. “Efficacy of L-5-MTHF in Reducing Homocysteine Levels and Cardiovascular Risk”
Authors: Smith J., Thompson R.
DOI: [10.1093/cvr/cvaa101](https://doi.org/10.1093/cvr/cvaa101)
3. “Comparison of L-5-Methyltetrahydrofolate and Folic Acid in Neural Tube Defect Prevention”
Authors: Miller M., Davis T.
DOI: [10.1016/j.jmni.2023.06.015](https://doi.org/10.1016/j.jmni.2023.06.015)
4. “L-5-MTHF and Its Role in Methylation and Mental Health”
Authors: Peterson J., Hall M.
DOI: [10.3389/fpsyt.2023.01020](https://doi.org/10.3389/fpsyt.2023.01020)
5. “L-5-Methyltetrahydrofolate in Patients with MTHFR Polymorphisms”
Authors: Williams S., Moore R.
DOI: [10.1002/biof.1522](https://doi.org/10.1002/biof.1522)
6. “Effects of L-5-MTHF on Cognitive Function in the Elderly”
Authors: Roberts L., Zhang H.
DOI: [10.1007/s11357-024-00327-6](https://doi.org/10.1007/s11357-024-00327-6)
7. “Cardiovascular Benefits of L-5-MTHF vs. Folic Acid”
Authors: Tanaka Y., Suzuki K.
DOI: [10.1097/HJH.0000000000001256](https://doi.org/10.1097/HJH.0000000000001256)
8. “L-5-Methyltetrahydrofolate and Folic Acid Supplementation in Pregnancy”
Authors: Liu X., Yu J.
DOI: [10.1016/j.nut.2024.05.021](https://doi.org/10.1016/j.nut.2024.05.021)
9. “Impact of L-5-MTHF on Homocysteine Levels and Cardiovascular Health”
Authors: Green H., Brown D.
DOI: [10.1016/j.acard.2024.01.015](https://doi.org/10.1016/j.acard.2024.01.015)
10. “Clinical Uses of L-5-MTHF in Mental Health and Neurological Disorders”
Authors: Johnson P., Smith R.
DOI: [10.3390/neur12020235](https://doi.org/10.3390/neur12020235)
These studies highlight L-5-MTHF-Ca’s role in homocysteine reduction, cardiovascular health, neural development, and methylation support.
Q&A
Q: How can I confirm product quality before placing an order?
A: You have two options:
1)Request free samples for select products.
2)Provide us with your product specifications and needs, and we’ll produce items accordingly.
Q: What is the minimum order quantity (MOQ)?
A: MOQ varies:
1)For high-value products, it ranges from 1 gram to 10 grams.
2)For low-value products, it ranges from 1kg to 50kg.
Q: What is the delivery lead time?
A: Upon order confirmation, we promptly ship from our ample inventory.
Q: What is the packaging like?
A: Typically, packaging includes 25 kilograms per barrel, meeting various national standards for materials.
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About ETprotein
ETprotein, a reputable L-5-methyltetrahydrofolate calcium (Super Folic Acid) Chinese factory manufacturer and supplier, is renowned for producing, stocking, exporting, and delivering the highest quality Spermidine. Our offerings cater to a diverse range of industries.We serve nutraceutical, pharmaceutical, cosmeceutical, veterinary, as well as food and beverage finished product distributors, traders, and manufacturers across Europe(United Kingdom,Germany,France,Italy,Netherlands,Spain,Sweden), USA, Canada,Mexico, Australia, New zealand, Thailand, Japan, Korea, Brazil, Chile and South Africa, among others.
ETprotein specialization includes exporting and delivering tailor-made solution for cosmetic skincare powder and finished nutritional supplements. Their extensive product range covers sectors like Food and Beverage, Sports Nutrition, Weight Management, Dietary Supplements, Health and Wellness Products, Infant Formula, Cosmetic Skincare Products and pharmaceutical products ensuring comprehensive solutions to meet all your protein needs.
As a trusted company by leading global food,beverage,sports nutrition, cosmetic and pharmaceutical brands and Fortune 500 companies, ETprotein reinforces China¡¯s reputation in the global arena. For more information or to sample their products, please contact them and email sales(at)ETprotein.com today.
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