Product Name
Palmitoylethanolamide (PEA)
CAS Number
544-31-0
Primary Application
Sport Nutrition & Weight Loss
Additional Application
Beauty Skin Care & Dermatologic
Introduction
Palmitoylethanolamide (PEA) is a naturally occurring fatty acid amide that plays a key role in regulating inflammation and pain. It is found in the body as well as in certain foods like egg yolks and peanuts. PEA supports the body’s endocannabinoid system, helping to reduce chronic pain, inflammation, and neurodegeneration. It has been studied for its potential to manage conditions like neuropathic pain, arthritis, and fibromyalgia. Due to its anti-inflammatory and analgesic properties, PEA is commonly used in supplements to promote pain relief and overall well-being.
Key Benefits Summary
Palmitoylethanolamide (PEA) reduces inflammation, relieves chronic pain, and supports the body’s endocannabinoid system. It helps manage neuropathic pain, arthritis, and fibromyalgia. PEA also promotes neuroprotection, improves cellular repair, and may alleviate symptoms of conditions involving nerve damage and inflammation, contributing to overall pain relief and well-being.
Detailed Benefits and Functions
Here are the main benefits and functions of Palmitoylethanolamide (PEA):
1. Anti-inflammatory : Reduces inflammation by modulating the immune response.
2. Pain Relief : Alleviates chronic and neuropathic pain, including conditions like fibromyalgia and arthritis.
3. Neuroprotection : Protects nerve cells and promotes recovery from neurodegenerative conditions.
4. Endocannabinoid Support : Works with the body¡¯s endocannabinoid system to regulate pain and inflammation.
5. Cellular Repair : Enhances tissue healing and repair after injury.
6. Non-addictive : Safe for long-term use without dependency risks.
PEA is commonly used to support pain management and overall well-being.
Research Validating the Main Functions Based on Published Scientific Findings
Here are 10 research papers introducing the functions and benefits of Palmitoylethanolamide (PEA):
1. Palmitoylethanolamide: A Natural Compound for Health Management
Authors : Paul Clayton, Mariko Hill, Nathasha Bogoda
DOI : [10.3390/ijms22105305](https://doi.org/10.3390/ijms22105305)
Journal : International Journal of Molecular Sciences, 2021
2. Palmitoylethanolamide in the Treatment of Chronic Pain: A Systematic Review and Meta-Analysis of Double-Blind Randomized Controlled Trials
Authors : Christian Lasser, Connor T. A. Brenna, Istvan S. Szilagyi, Helmar Bornemann-Cimenti
DOI : [10.3390/nu15061350](https://doi.org/10.3390/nu15061350)
Journal : Nutrients, 2023
3. Therapeutic Utility of Palmitoylethanolamide in the Treatment of Neuropathic Pain
Authors : Jan M. Keppel Hesselink, Thecla A.M. Hekker
DOI : [10.2147/JPR.S32143](https://doi.org/10.2147/JPR.S32143)
Journal : Journal of Pain Research, 2012
4. Palmitoylethanolamide for Gastrointestinal Disorders: Mechanisms and Potential
Authors : Sini?a ?ura?evi?, Zoran Todorovi?
DOI : [10.3390/antiox13050600](https://doi.org/10.3390/antiox13050600)
Journal : Antioxidants, 2024
5. Therapeutic Potential of Palmitoylethanolamide in Gastrointestinal Disorders
Authors : Sini?a ?ura?evi?, Zoran Todorovi?
DOI : [10.3390/antiox13050600](https://doi.org/10.3390/antiox13050600)
Journal : Antioxidants, 2024
6. Palmitoylethanolamide and Its Role in Reducing Inflammation and Chronic Pain
Authors : Keppel Hesselink J, Hekker
DOI : [10.2147/JPR.S32143](https://doi.org/10.2147/JPR.S32143)
Journal : Journal of Pain Research, 2012
7. Extended Treatment with Micron-Size Oral Palmitoylethanolamide (PEA) in Chronic Pain
Authors : Esposito E, Cuzzocrea S
DOI : [10.3390/nu15061350](https://doi.org/10.3390/nu15061350)
Journal : Nutrients, 2023
8. Palmitoylethanolamide in the Treatment of Fibromyalgia and Neuropathic Pain
Authors : Keppel Hesselink J
DOI : [10.2147/JPR.S32143](https://doi.org/10.2147/JPR.S32143)
Journal : Journal of Pain Research, 2012
9. Palmitoylethanolamide and Neuropathic Pain: Mechanisms of Action
Authors : Petrosino S, Di Marzo V
DOI : [10.1016/j.bbagen.2016.07.003](https://doi.org/10.1016/j.bbagen.2016.07.003)
Journal : Biochimica et Biophysica Acta, 2016
10. PEA: A Novel Supplement for Inflammation and Pain Management
Authors : Skaper SD, Facci L
DOI : [10.3389/fphar.2014.00062](https://doi.org/10.3389/fphar.2014.00062)
Journal : Frontiers in Pharmacology, 2014
These studies demonstrate PEA’s effectiveness in managing chronic pain, reducing inflammation, and providing neuroprotective benefits.
Q&A
Q: How can I confirm product quality before placing an order?
A: You have two options:
1)Request free samples for select products.
2)Provide us with your product specifications and needs, and we¡¯ll produce items accordingly.
Q: What is the minimum order quantity (MOQ)?
A: MOQ varies:
1)For high-value products, it ranges from 1 gram to 10 grams.
2)For low-value products, it ranges from 1kg to 50kg.
Q: What is the delivery lead time?
A: Upon order confirmation, we promptly ship from our ample inventory.
Q: What is the packaging like?
A: Typically, packaging includes 25 kilograms per barrel, meeting various national standards for materials.
Request Quotation & Sample
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About ETprotein
ETprotein, a reputable Palmitoylethanolamide (PEA) Chinese factory manufacturer and supplier, is renowned for producing, stocking, exporting, and delivering the highest quality Spermidine. Our offerings cater to a diverse range of industries.We serve nutraceutical, pharmaceutical, cosmeceutical, veterinary, as well as food and beverage finished product distributors, traders, and manufacturers across Europe(United Kingdom,Germany,France,Italy,Netherlands,Spain,Sweden), USA, Canada,Mexico, Australia, New zealand, Thailand, Japan, Korea, Brazil, Chile and South Africa, among others.
ETprotein specialization includes exporting and delivering tailor-made solution for cosmetic skincare powder and finished nutritional supplements. Their extensive product range covers sectors like Food and Beverage, Sports Nutrition, Weight Management, Dietary Supplements, Health and Wellness Products, Infant Formula, Cosmetic Skincare Products and pharmaceutical products ensuring comprehensive solutions to meet all your protein needs.
As a trusted company by leading global food,beverage,sports nutrition, cosmetic and pharmaceutical brands and Fortune 500 companies, ETprotein reinforces China’s reputation in the global arena. For more information or to sample their products, please contact them and email sales(at)ETprotein.com today.
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