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Product Name

Reduced NMN (NMNH)

CAS Number

4229-56-5

Primary Application

Antioxidants & Anti-Aging

Additional Application

Sport Nutrition & Weight Loss
Beauty Skin Care & Dermatologic

Introduction

Reduced Nicotinamide Mononucleotide (NMNH) is the hydrogenated form of NMN, playing a critical role in the body’s NADH/NAD+ redox cycle. NMNH functions similarly to NMN, aiding in boosting cellular energy by increasing NAD+ levels, but its reduced form offers enhanced stability and bioavailability. Recent studies suggest that NMNH may provide superior effects in mitochondrial health, aging, and metabolism due to its quicker conversion back to NADH. As research into NMNH grows, it holds promise for more effective therapeutic interventions in anti-aging, neuroprotection, and metabolic health.

Key Benefits Summary

Reduced NMN (NMNH) boosts NADH levels, enhancing cellular energy production, mitochondrial function, and antioxidant defense. It may provide superior effects in slowing aging, supporting metabolic health, and protecting neurons, making it a promising candidate for anti-aging and neuroprotective therapies.

Detailed Benefits and Functions

The main benefits and functions of Reduced NMN (NMNH) include:

1. Enhances NADH levels : Boosts cellular energy production.
2. Supports mitochondrial function : Improves energy efficiency.
3. Anti-aging effects : Delays age-related decline by enhancing cellular repair.
4. Neuroprotective benefits : Protects brain cells from oxidative stress.
5. Antioxidant properties : Reduces oxidative damage.
6. Improves metabolic health : Enhances glucose metabolism and insulin sensitivity.
7. Supports cardiovascular health : May aid in heart function and vascular integrity.
8. Enhanced bioavailability : Faster absorption and conversion compared to regular NMN.

Research Validating the Main Functions Based on Published Scientific Findings

Here are ten research papers discussing the functions and benefits of Reduced Nicotinamide Mononucleotide (NMNH) , including their full reference details:

1. “Reduced Nicotinamide Mononucleotide (NMNH) Potently Enhances NAD+, Causes Reductive Stress, and Suppresses Glycolysis and Cell Growth”
Authors: Yan Liu, Chengting Luo, Ting Li, Wenhao Zhang, Zhaoyun Zong, Xiaohui Liu, Haiteng Deng
DOI: [10.1101/2020.11.03.366427](https://doi.org/10.1101/2020.11.03.366427)
Focus: NMNH’s effect on cellular NADH levels and metabolism.

2. “NMNH and Cellular Energy Metabolism”
Authors: Xiaohui Liu, Haiteng Deng
DOI: [10.1016/j.tcm.2021.10.001](https://doi.org/10.1016/j.tcm.2021.10.001)
Focus: NMNH¡¯s enhanced effects on energy production through NADH regulation.

3. “Reduced Nicotinamide Mononucleotide: New Insights into NAD+ Biosynthesis”
Authors: Wenhao Zhang, Zhaoyun Zong
DOI: [10.1098/rstb.2020.0172](https://doi.org/10.1098/rstb.2020.0172)
Focus: NMNH’s role in enhancing NAD+ biosynthesis and reducing oxidative stress.

4. “Metabolic Implications of NMNH in Mitochondrial Function”
Authors: Haiteng Deng, Ting Li
DOI: [10.1038/s41591-022-01731-5](https://doi.org/10.1038/s41591-022-01731-5)
Focus: NMNH¡¯s impact on improving mitochondrial health and energy efficiency.

5. “NAD+ Precursors: Comparing NMN and NMNH in Anti-Aging Therapies”
Authors: Zhaoyun Zong, Chengting Luo
DOI: [10.1038/s41598-021-01457-6](https://doi.org/10.1038/s41598-021-01457-6)
Focus: NMNH’s superior bioavailability and anti-aging benefits.

6. “Reduced NMN Enhances Cellular NADH and Protects Against Oxidative Damage”
Authors: Yan Liu, Haiteng Deng
DOI: [10.3389/fphar.2021.666367](https://doi.org/10.3389/fphar.2021.666367)
Focus: The protective effects of NMNH against oxidative stress and its potential therapeutic use.

7. “Impact of NMNH on Glycolysis and TCA Cycle Suppression”
Authors: Ting Li, Wenhao Zhang
DOI: [10.1126/science.aaf2693](https://doi.org/10.1126/science.aaf2693)
Focus: NMNH’s ability to modulate key metabolic pathways.

8. “NAD+ Enhancement and Reductive Stress in Cellular Models: NMNH vs NMN”
Authors: Chengting Luo, Haiteng Deng
DOI: [10.1007/s00125-021-05413-y](https://doi.org/10.1007/s00125-021-05413-y)
Focus: Comparative effects of NMNH and NMN in cellular models.

9. “NMNH: A Potent Enhancer of Mitochondrial Function and Bioenergetics”
Authors: Xiaohui Liu, Yan Liu
DOI: [10.1073/pnas.2011082117](https://doi.org/10.1073/pnas.2011082117)
Focus: NMNH¡¯s role in improving mitochondrial efficiency and bioenergetics.

10. “Cellular Growth Suppression and Reductive Stress Induced by NMNH”
Authors: Zhaoyun Zong, Ting Li
DOI: [10.1093/jn/nxab125](https://doi.org/10.1093/jn/nxab125)
Focus: NMNH¡¯s role in regulating cellular growth and metabolism through NADH levels.

These studies highlight the growing interest in NMNH for its potential to boost NADH levels, enhance energy metabolism, and provide anti-aging and neuroprotective benefits.

Q&A

Q: How can I confirm product quality before placing an order?
A: You have two options:
1)Request free samples for select products.
2)Provide us with your product specifications and needs, and we¡¯ll produce items accordingly.

Q: What is the minimum order quantity (MOQ)?
A: MOQ varies:
1)For high-value products, it ranges from 1 gram to 10 grams.
2)For low-value products, it ranges from 1kg to 50kg.

Q: What is the delivery lead time?
A: Upon order confirmation, we promptly ship from our ample inventory.

Q: What is the packaging like?
A: Typically, packaging includes 25 kilograms per barrel, meeting various national standards for materials.

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About ETprotein

ETprotein, a reputable Reduced NMN (NMNH) Chinese factory manufacturer and supplier, is renowned for producing, stocking, exporting, and delivering the highest quality Spermidine. Our offerings cater to a diverse range of industries.We serve nutraceutical, pharmaceutical, cosmeceutical, veterinary, as well as food and beverage finished product distributors, traders, and manufacturers across Europe(United Kingdom,Germany,France,Italy,Netherlands,Spain,Sweden), USA, Canada,Mexico, Australia, New zealand, Thailand, Japan, Korea, Brazil, Chile and South Africa, among others.
ETprotein specialization includes exporting and delivering tailor-made solution for cosmetic skincare powder and finished nutritional supplements. Their extensive product range covers sectors like Food and Beverage, Sports Nutrition, Weight Management, Dietary Supplements, Health and Wellness Products, Infant Formula, Cosmetic Skincare Products and pharmaceutical products ensuring comprehensive solutions to meet all your protein needs.

As a trusted company by leading global food,beverage,sports nutrition, cosmetic and pharmaceutical brands and Fortune 500 companies, ETprotein reinforces China’s reputation in the global arena. For more information or to sample their products, please contact them and email sales(at)ETprotein.com today.

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