Keywords

Abstract

Abstract To evaluate the sobering activity of corn oligopeptides and curcumin on drunken mice when used alone or in combination, and to explore their mechanism of action. Clean-grade male KM mice were randomly divided into 4 groups, namely the model control group and low and medium levels. , high-dose group. Each dose group was administrated with the corresponding test substance, the corn oligopeptide model control group was administrated with the same amount of double-distilled water, and the curcumin model control group was administrated with double-distilled water containing 5.6% ethanol. After 0.5h, The two groups were gavaged with white wine (56¡ã). Behavioral indicators (disappearance time of righting reflex, duration of drunkenness, and clinging time) were measured immediately after the gavage. After 30 minutes, the concentrations of ethanol and acetaldehyde in the blood were measured, and the liver tissue was measured. Alcohol dehydrogenase (ADH), aldehyde dehydrogenase (ALDH), cytochrome P450 (CYP450), catalase (CAT), xanthine oxidase (XOD) and superoxide dismutase (SOD) activities. Compared with the model control group, corn oligopeptides can prolong the climbing time and righting reflex disappearance time of mice, shorten the time of drunkenness, and reduce the levels of ethanol and acetaldehyde in the blood. High-dose curcumin can significantly improve the behavior of mice after being drunk. Chemical indicators can reduce the concentration of ethanol and acetaldehyde in the blood to a certain extent. Both corn oligopeptides and curcumin can enhance the ADH and ALDH activities in mouse liver tissue, increase the contents of CYP450, CAT and SOD, and reduce the XOD activity. Corn oligopeptides When combined with curcumin, the activity against drunken mice was stronger than curcumin alone, but there was no significant difference from the group using corn oligopeptide alone. Under this experimental condition, corn oligopeptides and high-dose curcumin had an effect on drunken mice. Rats have obvious sobering activity

For further details regarding this article and its research, please do not hesitate to contact our team for assistance.

About ETprotein

ETprotein, a reputable plant protein vegan protein Chinese factory manufacturer and supplier, is renowned for producing, stocking, exporting, and delivering the highest quality organic bulk vegan protein and plant proteins. They include Organic rice protein, clear rice protein, pea protein, clear pea protein, watermelon seed protein, pumpkin seed protein, sunflower seed protein, mung bean protein, peanut protein etc. Their offerings, characterized by a neutral taste, non-GMO, allergen-free attributes, cater to a diverse range of industries. They serve nutraceutical, pharmaceutical, cosmeceutical, veterinary, as well as food and beverage finished product distributors, traders, and manufacturers across Europe, USA, Canada, Australia, Thailand, Japan, Korea, Brazil, and Chile, among others.

ETprotein specialization includes exporting and delivering tailor-made protein powder and finished nutritional supplements. Their extensive product range covers sectors like Food and Beverage, Sports Nutrition, Weight Management, Dietary Supplements, Health and Wellness Products, and Infant Formula, ensuring comprehensive solutions to meet all your protein needs.

As a trusted company by leading global food and beverage brands and Fortune 500 companies, ETprotein reinforces China’s reputation in the global arena. For more information or to sample their products, please contact them and email sales(at)ETprotein.com today.

Featured Products on Sale

Organic Brown Rice Protein

Protein: 80%, 85%,90%
NON-GMO, Solvents-free, Soy-free, Gluten-free, Low sodium, Low heavy metals, Pesticides free
Neutral taste, Lower fat, Longer shelf life
Organic COI/TC certificate is available for the European market
NOP import certificate is available for the USA/Canada market
Competitive price

Clear Rice Protein(Hydrolyzed Rice Protein)

Protein Min 85%
Neutral taste, win over all over the world’s existing competitors
Instant solubility in water, generates a clear solution, no sediments, and Stable for a longer shelflife

Pea Protein

Protein: 80%, 85%,90%
Neutral taste, Non-GMO, Solvents free, Soy-free, Gluten-free, Vegan, Low sodium,Lower heavy metals
Types for vegan meat, vegan beverage
Competitive price

Clear Pea Protein(Hydrolyzed Pea Protein)

Protein Min 85%
Neutral taste, win over all over the world’s existing competitors
Non-GMO, Solvents free, Soy-free, Gluten-free, Vegan, Low sodium, Lower heavy metals
Instant solubility in water, generates clear solution, no sediments, Stable for longer shelflife

Organic Pumpkin Seed Protein

Protein Min 70%
Neutral typical smooth taste, win over all over other existing competitors
NOP import certificate is available for the USA/Canada market

Contact sales@etprotein.com for a quotation and Free samples.

We’re excited to provide you with top-notch proteins and great customer service!